Benefits of Oral Rehydration on Orthostatic Intolerance in Children with Postural Tachycardia Syndrome (Journal of Pediatric Medicine)

normalyte was clinically proven to treat POTS patients more efficiently than IV alone

It's important to know the facts when you are treating patients for Postural Orthostatic Tachycardia Syndrome.  Here's what we know:

The WHO Recommendation

The World Health Organization has outlined the best methods t0 prevent dehydration in individuals with water loss due to chronic illnesses or acute illness like diarrhea.  Fairly recently the WHO outlined a new formula that has revolutionized the efficiency of rehydration.  Some have hailed it as the most significant discovery in modern medicine.

In the WHO's discovery there is a very specific recipe for oral rehydration.  You can read the white papers on ORS (oral rehydration salts) for dehydration here.

NormaLyte follows the WHO recommendations exactly.

NormaLyte is Clinically Studied

NormaLyte is clinically proven

In a clinical study, Oral Rehydration Salts like NormaLyte were proven to be more effective than saline IV alone.

Read the study details to determine if NormaLyte is a good solution for your patients, and view the charts below from the study:

 

Figure 1. 
The response of a representative patient with OI to the imposition of a controlled orthostatic challenge using LBNP. The top panel shows that in the absence of supplemental fluid administration (No Fluid), presyncope occurred during exposure to −30 mmHg negative pressure. Following IV saline (Saline, middle panel), and after ingestion of oral rehydration solution (ORS, lower panel), enhanced orthostatic tolerance was achieved as presyncope occurred during exposure to −60 mmHg negative pressure.
NormaLyte ORS clinical trial for POTS
Figure 2. 
Changes in cardiac output (CO in L/min) in control (top panel) and POTS patients with OI (bottom panel) during imposition of a controlled orthostatic challenge using LBNP following no treatment (No TX – white bars), IV sal ine (Saline – gray bars) and ingestion of oral rehydration solution (ORS – black bars). Treatment effects for controls were not significantly different. For POTS, CO was significantly higher following ORS, compared with no treatment (* = No Tx, p<0.05), both at baseline and −45mmHg and saline had no significant effect.
NormaLyte ORS clinical trial for POTS
Figure 3. 
Changes in normalized cerebral blood flow velocity (normalizedCBFV) in control (top panel) and POTS patients with OI (bottom panel) during imposition of a controlled orthostatic challenge using LBNP following no treatment (No TX – white bars), IV saline (Saline – gray bars) and ingestion of oral rehydration solution (ORS – black bars). Because there was no pressure effect, the comparisons reflect the combined effect (i.e., the weighted average) of the CBVv in the ORS group vs. No Tx. In controls, normalized CBFv was not significantly reduced at −45 mmHg, nor did fluid administration result in any significant change. In POTS, CBFv following ORS was significantly higher than No TX (ǂ = p<0.0005), which was independent of pressure.
NormaLyte ORS clinical trial for POTS
Figure 4. 
Changes in normalized orthostatic index (% of that measured without treatment in control (black bars) and POTS patients with OI (gray bars) measured following no treatment (Untreated), intravenous saline (IV Saline) and ingestion of oral rehydration solution (ORS). Neither saline nor ORS increased orthostatic tolerance in untreated controls (p=0.46, N=15); both I.V. saline and ORS significantly improved orthostatic tolerance (* = p<0.05 and ** = p<0.001, respectively, N=10) in POTS subjects.
NormaLyte ORS clinical trial for POTS

What is Postural Orthostatic Tachycardia Syndrome (POTS)

Postural Orthostatic Tachycardia Syndrome (POTS) is a form of dysautonomia that disrupts blood flow, causing symptoms like dizziness, rapid heart rate, fainting, fatigue, brain fog, and poor temperature regulation—often mistaken for anxiety.

How Normalyte Helps:

Dehydration can worsen POTS symptoms. Normalyte’s medical-grade Oral Rehydration Salts (ORS) are designed to restore hydration and balance electrolytes, helping reduce lightheadedness and fatigue.

First-time user?

Try a FREE sample of Normalyte ORS and feel the difference.

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Don't take our word for it

★★★★★

Just what I needed

I like the convenience of the capsules. I can get my sodium in all at once and early in the morning without having to drink a bunch of water plus a hydration pack to feel well. I’ve read some reviews that say these are horse pills, but they are absolutely not. They are smaller than my other supplements and I can take two at a time. I do need to take them with something in my stomach. Plus, the price is so much better than hydration packs from other brands.

Blythe Poston

Maryville, Illinois

★★★★★

Normalyte sodium/ potassium capsules

These work really well for my daughter. The salt tablets the dr prescribed made her really sick to her stomach. These have really helped with her POTS symptoms . Glad we discovered your product!

Patti Kenney

Kalamazoo, Michigan

★★★★★

These keep me going and able to be active. Helped stop having issues with seizures from dehydration (EDS/POTS related) and muscle spasms. So thankful to have found this product!

Carissa 

Portland, Oregon

★★★★★

Love these electrolytes capsules, improve my symptoms more than any other I’ve taken!

Madeline Denman

Chicago, Illinois

★★★★★

My Daughter finds these Helpful

I have these on auto-ship for my daughter - She finds them very helpful. The last two deliveries had a few broken capsules - which make it a little messy. Probably just a fluke...

CV 

Devon, Pennsylvania